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add to favorites Desonide CAS  638-94-8  for Anti-inflammatory Treatment (jerryzhang001@chembj.com) 211100 Other
Desonide CAS  638-94-8  for Anti-inflammatory Treatment

Desonide
English Synonyms: DESONIDE;1,4-PREGNADIEN-11-BETA, 16-ALPHA, 17,21-TETROL-3,20-DIONE 16,17-ACETONIDE;(11b,16a)-11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-pregna-1,4-diene-3,20-dione;16-alpha-hydroxyprednisole-16,17-acetonide;17-acetonide,16-alpha-hydroxy-prednisolone-1;d-2083;steroderm 
CAS NO.:  638-94-8 
Assay: 99%
Molecular Formula: C24H32O6 
Molecular Weight: 416.51 
Appearance: White powder
Packing:foil bag
Usage: With acetal-based adrenal cortex hormones
How to use s-desonide topical: Use this medication only on the skin.

Description:
Desonide is the generic name of a low-potency topical corticosteroid anti-inflammatory that has been available since the 1970s. It is primarily used to treat atopic dermatitis (eczema), seborrheic dermatitis, contact dermatitis and psoriasis in both adults and children. It has a fairly good safety profile and is available as a cream, ointment, lotion, and as a foam under the tradename Verdeso Foam. Other trade names for creams, lotions, and ointments include Tridesilon, DesOwen, Desonate. It is a group VI corticosteroid under US classification, the second least potent group.
Chemically, Desonide, the active ingredient in Desonide Ointment, 0.05% is C24H32O6. It has the following structural formula:
The molecular weight of Desonide is 416.51. It is a white to off-white powder. The solubility of Desonide in distilled water saturated with ether is 184 mg/L.
Each gram of Desonide Ointment, 0.05% contains 0.5 milligram of Desonide microdispersed in a base of white petrolatum.

Medical Function:
Desonide is a prescription topical treatment for redness, swelling, itching, and discomfort of various skin conditions. Regardless of the vehicle used, desonide is applied 2 to 3 times a day, at the same times each day. Skin conditions typically improve in the first two weeks of treatment. Patients are instructed to use desonide for the minimum amount of time necessary for conditions to improve.
Endogenous eczema clinical cure rate, the overall curative effect is distinct, and the low Incidence of adverse reactions, is a safe and effective external cortex hormone.
Wash your hands. Before applying the medication, clean and dry the affected area. Apply a thin film of the medication to the affected area and gently rub in, usually 2-3 times daily, or as directed by your doctor. If using the gel, apply the gel usually only 2 times daily. Do not bandage, wrap, or cover the area unless you are instructed to do so by your doctor. If used in the diaper area on an infant, do not use tight-fitting diapers or plastic pants.
After applying the medication, wash and dry your hands, unless you are using this medication to treat the hands. When applying this medication near the eyes, avoid getting it in the eyes because this may worsen or cause glaucoma, or cause irritation. Also, avoid getting this medication in the nose or mouth. If you get this medication in your eyes, nose, or mouth, rinse immediately with plenty of water.
add to favorites Ulipristal acetate CAS 126784-99-4  (jerryzhang001@chembj.com) 211100 Other
Ulipristal acetate CAS 126784-99-4 

Ulipristal acetate

Synonym: EllaOne, Ulipristal ace
CAS: 126784-99-4
M.F.: C28H35NO3
M.W.: 433.5824
Appearance: White crystalline powder
Usage: contraceptive medicine anabolic powder
Storage: Kept Ulipristal acetate in a cool, dry and ventilated place
We guarantee good quality products. 100% refunded if parcel is not delivered or poor quality.

Description
Ulipristal acetate (trade name EllaOne in the European Union, Ella in the U.S. for contraception, and Esmya for uterine fibroid) is a selective progesterone receptor modulator (SPRM).

Medical Uses
Emergency contraception:
For emergency contraception a 30 mg tablet is used within 120 hours (5 days) after an unprotected intercourse or contraceptive failure. It has been shown to prevent about 62–85% of expected pregnancies, and prevents more pregnancies than emergency contraception with levonorgestrel. Ulipristal acetate is available by prescription for emergency contraception in over 50 countries, with access through pharmacists without a prescription being tested in the United Kingdom. From July 2016 available without prescription in Israel.
Treatment of uterine fibroids
Ulipristal acetate is used for pre-operative treatment of moderate to severe symptoms of uterine fibroids in adult women of reproductive age in a daily dose of a 5 mg tablet.
Treatment of uterine fibroids with ulipristal acetate for 13 weeks effectively controlled excessive bleeding due to uterine fibroids and reduced the size of the fibroids.
Two intermittent 3-months treatment courses of ulipristal acetate 10 mg resulted in amenorrhea at the end of the first treatment course in 79.5%, at the end of the second course in 88.5% of subjects. Mean myoma volume reduction observed during the first treatment course (−41.9%) was maintained during the second one (−43.7%). After two to four 3-months courses of treatment, UPA-treated fibroids shown about -70% in volume reduction. This phenomenon was temptatively explained by the combination of multifactorial events involving control of proliferation of the tumor cells, induction of apoptosis and remodeling of the extracellular matrix.
add to favorites Tanning Skin Helpers Melanotan II CAS 121062-08-6 (jerryzhang001@chembj.com) 211100 Other
Tanning Skin Helpers Melanotan II CAS 121062-08-6

Melanotan II
 
Cas No.: 121062-08-6
Sequence: Ac-NLE-c[ASP-His-d-PHE-ARG-TRP-LYS]-NH2  Chemical Bridge Asp2-Lys7
Purity (HPLC): 98.0%
Appearance: White powder
Molecular Formula: C50H69N15O9
Molecular Weight: 1024.18
Single Impurity (HPLC): 0.5%max
Amino Acid Composition: ±10% of theoretical
Peptide Content (N%): ≥80.0%
Water Content(Karl Fischer): ≤8.0%
Acetate Content(HPIC): ≤10.0%
Specific Rotation (20/D): -55.0~-65.0°(c=1 1%HAc)
MS(ESI): Consistent
Mass Balance: 95.0~105.0%;

1. Description

Melanotan II is a cyclic lactam analog of the melanocortin alpha-Melanocyte Stimulating Hormone (alpha-MSH), a multifunctional peptide that regulates a broad array of physiological functions, including the stimulation of melanogenesis and aphrodisiac effects via melanocyte receptor activation.
It has been studied extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis stimulating properties.
Melanotan II could be used to stimulate skin melanogenesis and development as a photoprotective or cosmetic drug. Additionally, Melanotan II and a similar alpha-MSH analogue, know as PT-141 or Bremelanotide, have been studied at length as a potential remedy for the treatment of sexual dysfunction; specifically, male erectile dysfunction.

How it works?
This peptide is a designed to stimulate the body's tanning response with minimal exposure to sunlight. This can be a wonderful way for those with fair to very fair skin to get tanned without having to spend weeks in the sun and going through the burn and heal process.
By using MT2, users experience quicker tanning and and faster healing to damaged skin cells than would otherwise be possible. Because of this, it is especially suited to those who's skin is pale; those who are at greatest risk of developing skin cancer.

The Other Function:
Melanotan II may enhance sexual function in males (erectile activity) and females (increased levels of sexual desire and genital arousal). Unlike other sexual-enhancement drugs, it is hypothesizedd that Melanotan II works at a neurological level, eliciting a more "natural" sexual response with minimal side effects. 
add to favorites Estriol CAS 50-27-1 for  treating menopausal syndrom (jerryzhang001@chembj.com) 211100 Other
Estriol CAS 50-27-1 for  treating menopausal syndrom

Estriol
Synonyms: Oestriol; 1, 3, 5(10)-Estratriene-3, 16a, 17b-triol CAS: 979-32-8
CAS No.: 50-27-1
ECNECS No.: 200-022-2
MF: C18H24O3
MW: 288.3814
Purity: 99%min
Melting Point: 281-282º C
Boiling Point: 469 ºC at 760 mmHg
Refractive Index: 1.624
Flash Point: 220.8 ºC
Density: 1.255g/cm3
Appearance: White crystalline powder
Grade: Pharmaceutical Grade
Storage: Shading, confined preservation
Lead time: Within 12 hours upon receipt of payment
Delivery: EMS, DHL, TNT, FedEx, UPS
Usage: A metabolite of Estradiol. An estrogenic metabolite considerably less potent than the hormone Estradiol. Pharmaceutical material, Steroid hormone, estrogen.

2. Description
Estriol belongs to natural hormone and is the metabolite of estradiol in vivo. It is mainly presented in the urine. Estrogen has a relative small activity with the oral activity being 6 times as high as estrone but being weaker than estradiol with non-carcinogenic effects. After its administration, the in vivo estradiol levels did not change. 
Estriol has selective action on the vaginal and cervical canal but has no effect on the uterus and endometrium entity. Animal experiments have shown that estriol has a stronger effect on vaginal epithelial keratosis than estradiol, thus being able to promote vaginal epithelial hyperplasia, superficial cells keratosis, mucosal angiogenesis and vaginal epithelial wound healing, but having a weak effect on the weight gain of mouse uterus.
At the same time, estriol can enhance the function of cervix cell, causing the cervix muscle fiber hyperplasia and increasing the cervical elasticity and softness.
Estriol also has significant effect on the hematopoietic system and can reduce vascular permeability and fragility. Therefore, it can be used for the treatment of various kinds of hemorrhage. It also has effect of rapidly increasing the peripheral leukocytes and generally begins to take effect at 1 to 3 days after treatment but with a shorter duration of action and is effective in treatment the leukopenia induced by radiotherapy and chemotherapy. 

Medical Function
1.It can be used for treating cervicitis and especially suitable for treating menopausal syndrome and senile vaginitis. 
2. It can also be used as the adjuvant drug for middle-term labor induction and artificial abortion. 3. It can also be used for treating prostatic hypertrophy and prostate cancer.
4. It still has a rapid role in increasing the peripheral leukocytes. It generally takes effect at 1 to 3 days after the treatment but with a short duration period. It also has efficacy in treating leukopenia caused by chemotherapy or radiotherapy.
5. It can be used for reducing the vascular permeability and fragility and can be used for the treatment of various kinds of hemorrhage. It also has quick hemostasis effect on menorrhagia, hysterectomy or tonsillectomy.
2.Application:
It belongs to estrogen drug. It can be used for treating leukopenia, various kinds of menopathy, senile vaginitis, and menopausal syndrome. You may also get temporary breast swelling and lumps, menstrual cycle disorders with self-recovery after stopping the drug for about 1 month. Patients of breast hyperplasia, breast lumps, and cancer potentially being related to female hormone-related cancer, aplastic anemia and liver disease patients should be disabled.
add to favorites Dexamethasone CAS 50-02-2 for  inflammatory and autoimmune Treatment (jerryzhang001@chembj.com) 211100 Other
Super Pure 99% Dexamethasone CAS 50-02-2 for  inflammatory and autoimmune Treatment

1.Quick Detail:


Product name Dexamethasone
Other Name Fluormone; Fluorocort; Gammacorten; HL-Dex; Hexadecadrol; Hexadrol
Original China
CAS 50-02-2
ENIECS 200-003-9
Molecular formula C22H29FO5
MW 392.46
Brand name NJBNSteroid
Leading time within 24 hours upon receipt of payment
Delivery Fast and secure shipping by EMS, DHL, TNT, FedEx, UPS
Purity 98.8%
Package Discreet and Hidden package according to specific requirement
Appearance Off-White Powder
MP 262-264 °C
Certification SGS, ISO 9001, KOSHER
Payment Terms Western Union, Money Gram , T/T, Bitcoin
Minimum Order Quantity 5g
Price Negotiable
Usage Dexamethasone is a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthas e.

2. Description:
Dexamethasone is a type of steroid medication. It is used in the treatment of many conditions, including rheumatic problems, a number ofskin diseases, severe allergies, asthma, chronic obstructive lung disease,croup, brain swelling, and along with antibiotics in tuberculosis. In adrenocortical insufficiency it should be used together with a medication that has greater mineralocorticoid effects such as fludrocortisone. In preterm labor it may be used to improve outcomes in the baby. It may be taken by mouth, as an injection into a muscle, or intravenously. The effects of dexamethasone are frequently seen within a day and last for about three days.

The long term use of dexamethasone may result in thrush, bone loss, cataracts, easy bruising, or muscle weakness. It is pregnancy category C in the United States meaning use should be based on benefits being predicted to be greater than risks. In Australia it is class A, meaning it has been frequently used in pregnancy and not been found to cause problems to the baby. It should not be taken when breastfeeding.Dexamethasone has anti-inflammatory and immunosuppressant effects.


3.Application:
Dexamethasone is used to treat many inflammatory and autoimmune conditions, such as rheumatoid arthritis and bronchospasm. Idiopathic thrombocytopenic purpura, a decrease in numbers of platelets due to an immune problem, responds to 40 mg daily for four days; it may be administered in 14-day cycles. It is unclear whether dexamethasone in this condition is significantly better than other glucocorticoids.
Cancer patients undergoing chemotherapy are given dexamethasone to counteract certain side effects of their antitumor treatments. Dexamethasone can augment the antiemetic effect of 5-HT3 receptor antagonists, such as ondansetron.In brain tumors (primary or metastatic), dexamethasone is used to counteract the development of edema, which could eventually compress other brain structures. It is also given in cord compression, where a tumor is compressing the spinal cord.
Dexamethasone may be given to women at risk of delivering prematurely to promote maturation of the fetus' lungs. This has been associated with low birth weight, although not with increased rates of neonatal death.Dexamethasone has been also been used during pregnancy as an off-label prenatal treatment for the symptoms of congenital adrenal hyperplasia (CAH) in female fetuses. CAH causes a variety of physical abnormalities, notablyambiguous genitalia in girls. Early prenatal CAH treatment has been shown to reduce some CAH symptoms, but it does not treat the underlying congenital disorder.
Dexamethasone is the treatment for the very rare disorder of glucocorticoid resistance. In adrenal insufficiency and Addison's disease, dexamethasone is prescribed when the patient does not respond well to prednisone or methylprednisolone.
Dexamethasone is used in the treatment of high-altitude cerebral edema (HACE), as well as high-altitude pulmonary edema (HAPE). It is commonly carried on mountain-climbing expeditions to help climbers deal with complications of altitude sickness.
Dexamethasone and ondansetron are more effective than ondansetron alone in preventing postoperative nausea and vomiting.
add to favorites Prilocaine CAS 721-50-6 (jerryzhang001@chembj.com) 211100 Other
Prilocaine CAS 721-50-6

Synonyms: 2-(propylamino)-o-propionotoluidid;
CAS: 721-50-6
MF: C13H20N2O
MW: 220.31
EINECS: 211-957-0
Product Categories: Active Pharmaceutical Ingredients
Packing:Foil bag or as requirments;

Description

Prilocaine is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Löfgren. In its injectable form (trade name Citanest), it is often used in dentistry. It is also often combined with lidocaine as a topical preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia (IVRA).

Prilocaine belongs to amide local anesthetic drug with its anesthesia intensity and speed being similar as lidocaine but with a longer duration period and weaker effect on vasodilation. It has a lower toxicity than lidocaine. It is clinically for local anesthesia, especially suitable for treating patients who are not allowed to use adrenaline. 

In some patients, a metabolite of prilocaine may cause the unusual side effect of methemoglobinemia, which may be treated with methylene blue. 

Local anesthetic is a substance that causes loss of sensation only to the area to which it is applied without affecting consciousness. Most local anesthetics structures have amino-ester or an amino-amide group which are linked to hydrophilic (secondary or tertiary amine) and to hydrophobic group (aromatics) on the other side. 

Local anesthetics, long duration, lower toxicity, chemicals that are also small Suitable for epidural anesthesia, block anesthesia and infiltration anesthesia, etc. 

Application:
It is a kind of local anesthetic drug. The product has better efficacy than procaine and the local anesthesia intensity and speed being similar as lidocaine but with longer duration time and less toxicity as well as smaller accumulation effect. It is suitable for epidural anesthesia, conduction anesthesia and infiltration anesthesia.
add to favorites USP 32 Piroxicam CAS 36322-90-4 for Anti-inflammatory Treatment (jerryzhang001@chembj.com) 211100 Other
USP 32 Piroxicam CAS 36322-90-4 for Anti-inflammatory Treatment

Piroxicam
CAS: 36322-90-4
MF: C15H13N3O4S
MW: 331.35
EINECS: 252-974-3
Chemical Properties:White powder
Assay:99%
Active Pharmaceutical Ingredients; APIs; Piroxicam; All Inhibitors; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals; API's; Lipid signaling; Sulfur & Selenium Compounds.
Usage: Antipyretic analgesic active pharmaceutical ingredients.:Non-steroidal anti-inflammatory with long half-life. Cyclooxygenase inhibitor.
Packing:25kg/paper barrel or as required;

Description:
Piroxicam, in some countries. it is spelt piroksikam or piroxikam) is a non-steroidal anti-inflammatory drug (NSAID) of the oxicam class used to relieve the symptoms of painful, inflammatory conditions like arthritis. Piroxicam works by preventing the production of a certain type of body chemical called prostaglandins which are involved in the mediation of pain, stiffness, tenderness and swelling.The medicine is available as capsules, tablets and (not in all countries) as a prescription-free gel 0.5%. It is also available in a betadex formulation, which allows a more rapid absorption of piroxicam from the digestive tract.
Application:
Piroxicam is used to reduce pain, swelling, and joint stiffness from arthritis. Reducing these symptoms helps you do more of your normal daily activities. This medication is known as a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking your body's production of certain natural substances that cause inflammation.
If you are treating a chronic condition such as arthritis, ask your doctor about non-drug treatments and/or using other medications to treat your pain. See also Warning section.
add to favorites Tranexamic Acid CAS 1197-18-8 (jerryzhang001@chembj.com) 211100 Other
Tranexamic Acid CAS 1197-18-8

Synonyms: Trans-4-Aminomethylcyclohexane-1-carboxylate; Trans-4-(Aminomethyl)cyclohexanecarboxylic acid; Amstat
CAS: 1197-18-8
EINECS No.: 212-818-4
M. F.: C8H15NO2
M. W.: 157.21
Assay: 99.0-101.0%
Apperance: White crystalline Powder
Type: Anesthetic Agents
Grade Standard: Cosmetic Grade, Medicine Grade
PH: 7.0~8.0
Chloride: 140ppm max
Loss on drying: 0.5%max
Sulfated ash: 0.1%max
Use: Hemostatic effect; (for pharmaceutical and cosmetic use)
Packing: 1kg Aluminum foil bag or 25kg fiber drum;

Description
Tranexamic acid (TXA) is a medication used to treat or prevent excessive blood loss from trauma, surgery, and in various medical conditions including hemophilia and heavy menstrual bleeding. It comes in oral and intravenous forms.
Tranexamic acid is an antifibrinolytic that competitively inhibits the activation of plasminogen to plasmin, a molecule responsible for the degradation of fibrin. Fibrin is the basic framework for the formation of a blood clot in hemostasis.Tranexamic acid has roughly 8 times the antifibrinolytic activity of an older analogue.
Function:
A- For fibrinolytic hemorrhages, such as brain, lung, uterine, the prostate gland, adrenal gland, thyroid gland, trauma or surgical bleeding.
B- Intraoperative early medication or preoperative medication, can reduce bleeding in the operation, and decrease the amount of blood transfusion.
C- Also used in pulmonary hemorrhage, liver cirrhosis hemorrhage and upper gastrointestinal hemorrhage.
D- Used in bleeding caused by fibrinolysis process hyperfunction:
Such as abnormal bleeding of operation for the lung, liver, pancreas, prostate, thyroid, adrenal surgery.
Such as obstetrics and postpartum hemorrhage and tuberculosis hemoptysis or blood-stained sputum, hematuria, prostatic hypertrophy bleeding, upper gastrointestinal bleeding, etc.
E- Can also be used for bleeding caused by excessive streptokinase or urokinase.

Medical Uses
1.Hemostatic, significant effect on traumatic bleeding, preoperative prophylactic medication can decrease operation hemorrhage.
2. The chemical structure of tranexamic acid and lysine, competitive inhibition of plasminogen to fibrin adsorption, to prevent their activation, protect the fiber protein was not degraded by the enzyme and dissolved, ultimately achieve hemostasis effect.
3. All applicable in the treatment of acute or chronic, localized or systemic primary fibrinolysis hyperfunction caused by bleeding, such as obstetric hemorrhage, renal hemorrhage, hypertrophy of the prostate, hemophilia hemorrhage, pulmonary tuberculosis hemoptysis, bleeding in the stomach, liver, lung, spleen and other organs of hemorrhage after operation
4. The clinical effect of tranexamic acid on insect bites, eczema and dermatitis, simple purpura, chronic urticaria, artificial sex urticaria, rash and drug poisoning effect, also have certain effects on erythroderma, scleroderma, SLE, erythema multiforme, herpes zoster and alopecia areata, curative effect of hereditary angioedema is also good.
add to favorites Acitretin CAS 55079-83-9 (jerryzhang001@chembj.com) 211100 Other
Acitretin CAS 55079-83-9

Chemical information
Product name:Acitretin
CAS No.:55079-83-9
Molecular formula:C21H26O3
Molecular weight:326.43
Product Specifications:Pharmacopoeial grade

Specification:
Product name: Acitretin
Other Name (all-e)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraen;6,8-nonatetraenoicacid,3,7-dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-4;all-trans-3,7-dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-2,4,6,8-nonatetra;all-trans-etretin;retinoidetretin;ro10-1670;(E)-9-(4-METHOXY-2,3,6-TRIMETHYLPHENYL)-3,7-DIMETHYL-2,4,6,8-NONATETRAENOIC ACID;etretin
Original China
CAS 55079-83-9
EINECS 259-474-4
Molecular formula C21H26O3
Molecular Weight 326.43
Brand name NJBNSteroid
Delivery time within 24 hours upon receipt of payment
Delivery Fast and secure shipping by EMS, DHL, TNT, FedEx, UPS
Purity 99%
Package Discreet and Hidden package according to specific requirement
Appearance Yellow powder
Certification SGS, ISO 9001, KOSHER
Payment Terms Western Union, Money Gram , T/T, Bitcoin
Minimum Order Quantity 10g
Price Negotiable
Usage It is typically used for psoriasis;


Description
Acitretin (trade names Soriatane and Neotigason) is a second-generation retinoid. It is taken orally, and is typically used for psoriasis.
It is a metabolite of etretinate, which was used prior to the introduction of acitretin. Etretinate was discontinued because it had a narrow therapeutic index as well as a long elimination half-life (t1/2=120 days), making dosing difficult. In contrast, acitretin's half-life is approximately 2 days. However, because acitretin can be reverse metabolised into etretinate which has an extremely long half-life, women must avoid becoming pregnant for at least 3 years after discontinuing acitretin. Therefore, acitretin is generally not recommended for women of child-bearing age with a risk of becoming pregnant.

Medical Uses:
Acitretin is an oral retinoid used in the treatment of severe resistant psoriasis. Because of the potential for problems and severe side effects it is generally used in only very severe cases of psoriasis that have been unresponsive to other treatments. It binds to nuclear receptors that regulates gene transcription. They induce keratinocyte differentiation and reduce epidermal hyperplasia, leading to the slowing of cell reproduction. Acitretin is readily absorbed and widely distributed after oral administration. A therapeutic effect occurs after 2 to 4 weeks or longer.
Patients that have received the medication are advised against giving blood for at least 3 years due to the risk of birth defects.
add to favorites Tetracaine CAS 14252-80-3 (jerryzhang001@chembj.com) 211100 Other
Tetracaine CAS 14252-80-3

Product name:Tetracaine
CAS No.: 14252-80-3
EINECS No.: 241-917-8
MF: C18H31ClN2O2
MW: 342.9
Appearance: White crystal powder
Purity: 98.5%~101.5%
Ash: 0.1% max
Loss on dry: 0.1% max
Heavy Metal: 10ppm max

Tetracaine (also known as amethocaine) is a local anesthetic of the ester anesthetic group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.

Description

Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.

Tetracaine is the T in Tac, a mixture of 5 to 12 per cent tetracaine, 5M(per myriad), a half per mille (0.5‰), or .05 per cent (1 part in 2000) , and 4 or 10 per cent hydrochloride used in ear, nose & throat surgery and in the emergemcy department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive locations.

Tetracaine is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.

Usage:

Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
 
In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
add to favorites Anxiolytic Injectable Hormones Selank Polypeptide 5mg/vial reliever of anxiety (jerryzhang001@chembj.com) 211100 Other
Anxiolytic Injectable Hormones Selank Polypeptide 5mg/vial reliever of anxiety


Selank
Alias: Selanc
Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro
MF: C33H57N11O9
MW: 751.9
Purity: 99%
Specification: 5mg/vial
Appearance: White Powder
Place of Origin: China
Standard: USP
Certification: SGS
Method of Analysis: HPLC
Packaging Details: Very discreet. As required.

2. What is Selank ?
Selank  is a nootropic, anxiolytic peptide based drug developed by the Institute of Molecular Genetics of the Russian Academy of Sciences. Selank is a heptapeptide with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro. It is a synthetic analogue of a human tetrapeptide tuftsin.
Neuropeptide Selank is a synthetic derivative of the human body's naturally produced tetrapeptide Tuftsin. Selank is used as an anxiolytic in the therapy of anxiety and phobic disorders, including generalized anxiety. Its action is similar to that of mild benzodiazepins but without the sedative effects. As a selective anxiolytic with a nootropic component, Selank can be used as treatment of depression, fear and general anxiety. It also reduces phsychic tension.

Medical Application:
Selank is classified as a nootropic-anxiolytic type drug, it uses extend beyond the relief of anxiety and improved cognitive functioning alone. A few areas in which Selank may find itself useful are: Stress reduction, the alleviation of depression, reversal of anhedonia, improvement in mood in emotionally stable individuals, and cessation of insomnia. Of course, with Selank being a nootropic-anxiolytic, it also prove useful for the treatment of different forms of anxiety, such as G. A. D (generalized anxiety disorder), S. A. D (social anxiety disorder), Panic Disorder, as well as non-diagnosed bouts of anxiety. As a nootropic, Selank can help enhance mental sharpness, reduce mental fatigue, improve the ability to focus, improve cognitive functioning while in a sleep deficit, and enhance memory.
add to favorites Ropivacaine hydrochloride CAS 132112-35-7  (jerryzhang001@chembj.com) 211100 Other
Ropivacaine hydrochloride CAS 132112-35-7 
 
Synonyms: S-ROPIVACAINE HCL;(S)-ROPIVACAINE HYDROCHLORIDE;ROPIVACAINE HYDROCHLORIDE MONOHYDRATE;ROPIVCACAINE HYDROCHLORIDE;ROPIVACAINE HCL;(S)-1-propyl-2',6'-dimethylanilinoformoxylpiperidine monohydrochloride monohydrate;(S)-1-propyl-2',6'-dimethylanilinoformoxylpiperidine,monohydrochloride,monohydrate;(S)-Ropivaxaine hydrochloride 
CAS: 132112-35-7 
MF: C17H26N2O.ClH.H2O 
MW: 328.88 ;

Description
Ropivacaine is a local anaesthetic drug belonging to the amino amide group. The name ropivacaine refers to both the racemate and the marketed S-enantiomer. Ropivacaine hydrochloride is commonly marketed by AstraZeneca under the trade name Naropin.

Medical Uses:
Ropivacaine is indicated for local anaesthesia including infiltration, nerve block, epidural and intrathecal anaesthesia in adults and children over 12 years. It is also indicated for peripheral nerve block and caudal epidural in children 1–12 years for surgical pain. It is also sometimes used for infiltration anaesthesia for surgical pain in children.
Ropivacaine is often coadministered with fentanyl for epidural analgesia, for example in pregnant women during labour.
add to favorites Promethazine hydrochloride CAS 58-33-3 (jerryzhang001@chembj.com) 211100 Other
Promethazine hydrochloride CAS 58-33-3


Promethazine HCl
Product Name: Promethazine hydrochloride
Promethazine HCl CAS: 58-33-3
Promethazine HCl MF: C17H21ClN2S
Promethazine HCl MW: 320.88
Promethazine HCl EINECS: 200-375-2
Promethazine HCl MP: 230-232 °C
Promethazine HCl Storage: Temp. Refrigerator
Promethazine HCl Merck: 13, 7878
Promethazine HCl Apperance: White Solid
Promethazine HCl Usage: Antihistaminic, antiemetic, CNS depressant; Stool softener;


Medical Uses:

Promethazine is used to prevent and treat nausea and vomiting related to certain conditions (such as before/after surgery, motion sickness). It is also used to treat allergy symptoms such as rash, itching, and runny nose. It may be used to help you feel sleepy/relaxed before and after surgery or to help certain narcotic pain relievers (such as meperidine) work better. It may also be used for a short time to treat a runny nose due to the common cold.

Promethazine is an antihistamine and works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction. Its other effects (such as anti-nausea, calming, pain relief) may work by affecting other natural substances (such as acetylcholine) and by acting directly on certain parts of the brain.
add to favorites Procaine hydrochloride CAS 51-05-8 for Pain Relieving (jerryzhang001@chembj.com) 211100 Other
Procaine hydrochloride CAS 51-05-8 for Pain Relieving

Product Name Procaine hydrochloride
Molecular Formula C13H21ClN2O2
Molecular Weight 272.771
CAS Registry Number 51-05-8
EINECS 200-077-2
Appearance: White crystalline powder;

Application:
 
Procaine HCl is a local anesthetic drug of the amino ester group.It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry.Owing to the ubiquity of the trade name Novocain, in some regions procaine is referred to generically as novocaine.It acts mainly by being a sodium channel blocker.Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.

Procaine HCl is indicated for the production of local or regional analgesia and anesthesia by local infiltration and peripheral nerve block techniques.

Application of procaine leads to the depression of neuronal activity.The depression causes the nervous system to become hypersensitive producing restlessness and shaking, leading to minor to severe convulsions.Studies on animals have shown the use of procaine led to the increase of dopamine and serotonin levels in the brain.Other issues may occur because of varying individual tolerance to procaine dosage.Nervousness and dizziness can arise from the excitation of the central nervous system, which may lead to respiratory failure if overdosed.Procaine may also induce weakening of the myocardium leading to cardiac arrest.

Procaine can also cause allergic reactions causing the individuals to have problems with breathing, rashes, and swelling.Allergic reactions to procaine are usually not in response to procaine itself, but to its metabolite PABA.About one in 3000 people have an atypical form of pseudocholinesterase,[citation needed] which does not hydrolyze ester anesthetics such as procaine, resulting in a prolonged period of high levels of the anesthetic in the blood and increased toxicity.


How it works?

Procaine Hydrochloride is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. In addition, this agent increases electrical excitation threshold, reduces rate of rise of action potential and slows nerve impulse propagation thereby causing loss of sensation.
add to favorites Tetracaine CAS 94-24-6 for Pain Relieving (jerryzhang001@chembj.com) 211100 Other
Tetracaine CAS 94-24-6 for Pain Relieving

Product Name:Tetracaine
Synonym:Anetain, Amethocaine, Pontocaine,Ametop,Dicaine
CAS:94-24-6
MF:C15H24N2O2
MW:264.36
EINECS:202-316-6
Assay:99%
Quality Standards:Enterprise Standard/Pharma Grade
AppearanceWhite powder
Package25kg/Drum
Usage: Tetracaine is a topical local anesthetic for the eyes. Tetracaine works by interfering with entry of sodium ions into nerve cells. This reduces the ability of nerves to generate an impulse and send pain sensations.

Tetracaine (also known as amethocaine) is a local anesthetic of the ester anesthetic group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.


Usage:

Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
 
In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
 
A systematic review investigated tetracaine for use in emergency departments, especially for IV cannulation in children, in view of its analgesic and cost-saving properties. However, it did not find an improvement in first attempt cannulations.
add to favorites Pramipexole CAS 104632-26-0 (jerryzhang001@chembj.com) 211100 Other
Pramipexole CAS 104632-26-0

Synonyms: Mirapex, Mirapexin, Sifrol;

CAS Number: 104632-26-0
Molecular Weight: 211.324 g/mol
Molecular Formula: C10H17N3S
Appearance: white crystalline powder;
add to favorites Oxytocin CAS 50-56-6 (jerryzhang001@chembj.com) 211100 Other
Oxytocin CAS 50-56-6

Basic Details:
Product Name: Oxytocin
Synonyms: A-HYPOPHAMINE
CAS:    50-56-6
MF:    C43H66N12O12S2
MW:    1007.19
EINECS:    200-048-4
Purity (HPLC): 98.0%min.
Single Impurity (HPLC): 1.0%max
Amino Acid Composition: ±10% of theoretical
Peptide Content (N%): ≥80.0%
Water Content(Karl Fischer): ≤6.0%
Acetate Content(HPIC): ≤12.0%
MP:  192-194 °C
BP:  1533.3°C at 760 mmHg
FP:  881.1°C
Storage temp:  2-8°C
Appearance: white powder
Density: 1.27 g/cm3
Storage: Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18° C. Upon reconstitution of the peptide it should be stored at 4° C between 2-21 days and for future use below -18° C.

1. Description
Oxytocin is also called Pitocin, is a kind of uterine contraction medicine, can be extracted from animal posterior pituitary or chemical synthesis, chemical synthesis including on vasopressin, no booster effect, selective excitate uterine smooth muscle, strengthen its contracting, uterus is most sensitive to oxytocin (estrogen secretion increase) when parturient,  immature uterus have no reactivity to this product, pregnancy early or middle uterine have low reactivity to oxytocin, late pregnancy is gradually increased, and before the antepartum, the reactivity is the highest.

How to Use?
Oral invalid, easily destroyed by digestive juice, but can be oral cavity mucous membrane absorption, intravenous drip 0.01 IU can cause uterine physiological contraction in 1 ~ 3 minutes (rhythmicity, polarity, symmetry), hold time is short, the half-life is only 2.5 ~ 3 minutes high-dose make uterine muscle is tetanic contraction. Have synergy effect with prostaglandin.

Medical Function:
Small dose can strengthen the smooth muscle contraction rhythm at the bottom of the uterine, to reinforce the contraction force, contraction frequency, shrinkage properties similar to those in natural birth, and keep the polarity and symmetry, so the clinical used in hastening parturition, inducing abortion. Large dose make uterine muscle tetanic contraction, clinical to oppression blood vessels between muscle fibers, to prevent and treatment of postpartum hemorrhage and postpartum subinvolution, and has the effect to promote lactation, the breast duct contraction, prompting milk from the breast. Larger dose is also used in postpartum hemorrhage, the afterbirth not out, etc.
add to favorites Obeticholic Acid CAS 459789-99-2  (jerryzhang001@chembj.com) 211100 Other
Obeticholic Acid CAS 459789-99-2 


Product Name: Obeticholic Acid
CAS: 459789-99-2 
MF: C26H44O4 
MW: 420.63 
density  1.091 
Appearance : White powders
Purity : 99%
Package : 1kg/foil bag 
Related categories: pharmaceutical intermediates; pharmaceutical raw materials; Aobei acid;  API
Usage : Obeticholic Acid is a potent and selective farnesoid X receptor (FXR) agonist with EC50 of 99 nM.

Omeprazole (Prilosec, Zegerid) belongs to group of drugs called proton pump inhibitors. It decreases the amount of acid produced in the stomach.
Omeprazole is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions caused by excess stomach acid. It is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).

Medical application

Omeprazole can be used in the treatment of gastroesophageal reflux disease (GERD), peptic ulcers, erosive esophagitis, and Zollinger-Ellison syndrome.

Peptic ulcers may be treated with omeprazole. Treatment of H. pylori infection can be completed by taking a triple therapy combination of omeprazole, amoxicillin, and clarithromycin for 7–14 days. Amoxicillin may be replaced with metronidazole in patients who are allergic to penicillin.
Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).
If you are self-treating with this medication, over-the-counter omeprazole products are used to treat frequent heartburn (occurring 2 or more days a week). Since it may take 1 to 4 days to have full effect, these products do not relieve heartburn right away.
add to favorites Obeticholic Acid CAS 459789-99-2  (jerryzhang001@chembj.com) 211100 Other
Obeticholic Acid CAS 459789-99-2 


Product Name: Obeticholic Acid
CAS: 459789-99-2 
MF: C26H44O4 
MW: 420.63 
density  1.091 
Appearance : White powders
Purity : 99%
Package : 1kg/foil bag 
Related categories: pharmaceutical intermediates; pharmaceutical raw materials; Aobei acid;  API
Usage : Obeticholic Acid is a potent and selective farnesoid X receptor (FXR) agonist with EC50 of 99 nM.

1. What is Dibucaine hydrochloride ?

Obeticholic acid (abbreviated to OCA), is a semi-synthetic bile acid analogue which has the chemical structure 6α-ethyl-chenodeoxycholic acid. It has also been known as INT-747. It is undergoing development as a pharmaceutical agent for several liver diseases and related disorders. Intercept Pharmaceuticals Inc. (NASDAQ symbol ICPT) hold the worldwide rights to develop OCA outside Japan and China, where it is licensed to Dainippon Sumitomo Pharma.

Medical application:

Obeticholic acid is a prescription medication used to treat primary biliary cholangitis. 
Obeticholic acid is a semi-synthetic derivative of bile acid. This drug works by binding to a receptor in the liver, intestines, kidney, and adipose tissue and changing the body’s metabolism of lipids.
This medication is available as a tablet and is typically taken once a day, with or without food. 
Common side effects of obeticholic acid include itching, fatigue, stomach pain, joint pain, throat pain, and constipation. Obeticholic acid may cause dizziness. Do not drive or operate heavy machinery until you know this medication affects you. 
add to favorites Noopept CAS 157115-85-0 as cognitive enhancer (jerryzhang001@chembj.com) 211100 Other
Noopept CAS 157115-85-0 as cognitive enhancer

Noopept is one of the most effective and strongest of all the Nootropic supplements on the market today.
It has been found improve memory, learning capacity, focus, and concentration.

Product Name: Noopept
Alias: N-(1-(Phenylacetyl)-L-prolyl)glycine ethyl ester
CAS No.: 157115-85-0
Molecular Formula: C17H22N2O4
Assay: 99%
Appearance: White crystalline powder
Grade Standard: Food Grade, Medicine Grade
Storage: Shading, confined preservation
Place of Origin: China
Brand name: NJBN STEROID
Certification: SGS.

Description:
Noopept, a strong cognitive enhancer, was developed in Russia in the early 2000s for the treatment of alcohol induced brain damage. A mind-turning supplement, Noopept is a powerful substance which is able to cross the blood brain barrier. It works primarily by binding to glutamate receptors and exerting strong neuroprotective effects on the brain. Its high bio-availability also means it is fast acting and may have a cumulative effect.

While it is most well known as a brain supplement, Noopept also increases coordination and improves mood. It is able to help fight fatigue and avoid caffeine withdrawals with no noticeable side effects. It makes a great study aid, since it will not cause insomnia. Some research also indicates that this supplement may help to prevent oxidization damage to the brain. It also works to treat alcohol related brain damage (this was actually the original purpose for its development).

Benefit:
Most people turn to Noopept because they are hoping to increase their brainpower and experience cognitive enhancement.
Certainly, a number of users and studies have shown that this can be very effective at increasing memory and learning abilities.
Speed of memory recall may also be improved.
Mental energy is also improved. This can be compared to lifting a type of brain fog. Everything will become more clear and require less thought when supplementing with Noopept. Attention span is improved along with greater concentration and focus.
The supplement is also important for supporting overall brain health. Noopept is actually considered a neuroprotectant, meaning that it has the ability to help protect the neurons in the brain from damage.
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