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add to favorites CAS 61-12-1 Local Anaesthesia Drugs Dibucaine Hydrochloride / Dibucaine HCL (jerryzhang001@chembj.com) 211100 Other
CAS 61-12-1 Local Anaesthesia Drugs Dibucaine Hydrochloride / Dibucaine HCL

Dibucaine hydrochloride
CAS:61-12-1
EINECS number:200-498-1
Molecular formula: C20H31Cl2N3O2
Molecular weight:416.385
MP:99-101 º C
Boiling point:544.7 ° C at 760 mmHg
Flash Point:283.2 ° C
Vapor Pressure:3.37E-12mmHg at 25 ° C
Properties:
MP 99-101 ° C
Product use:
Use:Anesthetic (local),Pharmaceutical raw materials;

1. What is Dibucaine hydrochloride ?
Dibucaine hydrochloride is a local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted. The drug blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade. 

In combination sodium dibucaine hydrochloride is administered to dogs to induce rapid, humane, painless euthanasia. The euthanasia solution is toxic to wildlife. Euthanized animals must be properly disposed of by deep burial, incineration or other method in compliance with state and local laws.

Medical Uses:

Dibucaine Hydrochloride - A local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia.
 
(From Martindale, The Extra Pharmacopoeia, 30th ED, p1006) Indication: For production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks. Dibucaine Hydrochloride is an amide-type local anesthetic, similar to lidocaine.
add to favorites Pramoxine Hydrochloride CAS 637-58-1 (jerryzhang001@chembj.com) 211100 Other
Pramoxine Hydrochloride CAS 637-58-1
CAS: 637-58-1
EINECS number: 211-293-1
Molecular formula: C17H28ClNO3
Molecular Weight: 329.8621
Boiling point: 427 ° C at 760 mmHg
Flash Point: 123.5 ° C
Vapor Pressure: 1.7E-07mmHg at 25 ° C
Appearance: White or almost white crystalline powder
Uses:Surgical anesthesia:Epidural anesthesia (including epidural anesthesia during cesarean section);Local infiltration anesthesia. 
Acute pain control:For postoperative or labor analgesia continuous epidural infusion can be used can also be intermittent medication;Local infiltration anesthesia.

1.Description

Pramocaine (INN and BAN, also known as pramoxine or pramoxine HCI) is a topical anesthetic discovered at Abbott Laboratories in 1953 and used as an antipruritic. Chemically, it is p-n butoxyphenyl gammamorpholinopropyl ether hydrochloride.
 Pharmacologic study revealed it to be potent and of low acute and subacute toxicity, well tolerated by most mucous membranes and of a low sensitizing index in humans.Like other local anesthetics, paramoxine decreases the permeability of neuronal membranes to sodium ions, blocking both initiation and conduction of nerve impulses. Depolarization and repolarization of excitable neural membranes is thus inhibited, leading to numbness.
The popular itch creams Gold Bond and some forms of Calamine Lotion use pramocaine hydrochloride to numb sensitive skin, as does the pain relief variant of Neosporin and some formulations of Sarna. The hydrochloride salt form of pramocaine is water-soluble.
Medical Application:
Pramoxine belongs to a class of drugs known as local anesthetics. It works by numbing the skin to block the feelings of pain and itching.
Pramoxine is used to temporarily relieve itching and pain caused by minor skin irritation such as minor burns/cuts/scrapes, sunburn, eczema, insect bites, cold sores, or rashes from poison ivy, poison oak, or poison sumac. Some products containing pramoxine are also used to temporarily relieve the itching and discomfort from hemorrhoids and certain other problems of the genital/anal area (such as anal fissures, itching around the vagina/rectum).
add to favorites Tetracaine hydrochloride CAS 136-47-0 (jerryzhang001@chembj.com) 211100 Other
Tetracaine hydrochloride CAS 136-47-0

Tetracaine hydrochloride
English Synonyms:
L AND OCAIN HYDROCHLORIDE;INTERCAIN HYDROCHLORIDE;MEETHOBALM HYDROCHLORIDE;2-(DIMETHYLAMINO)ETHYL 4-(N-BUTYLAMINO)BENZOATE HYDROCHLORIDE;2-DIMETHYLAMINOETHYL ESTER OFP-BUTYLAMINOBENZOIC ACID HYDROCHLORIDE;4-(N-BUTYLAMINO)BENZOIC ACID 2-(DIMETHYLAMINO)ETHYL ESTER HYDROCHLORIDE;4-[BUTYLAMINO]BENZOIC ACID-2-[DIMETHYLAMINO]ETHYL ESTER HYDROCHLORIDE;4-BUTYLAMINOBENZOIC ACID DIMETHYLAMINOETHYL ESTER HCL
CAS NO.: 136-47-0
EINECS: 205-248-5
Assay: 98%
Molecular Formula: C15H25ClN2O2
Molecular Weight: 300.82
Quality Standard: USP31
Packing: foil bag/tin
Usage: A local anesthetic used topically in opthalmology.

2. What is Tetracaine HCl?
Tetracaine (also known as amethocaine) is a local anesthetic of the ester anesthetic group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
Tetracaine is the T in TAC, a mixture of 5 to 12 per cent tetracaine, 0.05 per cent adrenaline, and 4 or 10 percent cocaine hydrochloride used in ear, nose & throat surgery and in the emergency department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive locations.
It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

Medical Uses:

It is taken as Spinal anesthesia (high, low, saddle block) and topically to produce surface anesthesia:
Eye: To anesthetize conjunctiva and cornea prior to superficial procedures (including tonometry, gonioscopy, removal of foreign bodies or sutures, corneal scraping).
Nose and Throat: To abolish laryngeal and esophageal reflexes prior to bronchoscopy, esophagoscopy. 
Skin: To relieve pruritus, pain, burning.
add to favorites Ropivacaine hydrochloride CAS 132112-35-7   (jerryzhang001@chembj.com) 211100 Other
Ropivacaine hydrochloride CAS 132112-35-7 
 
Synonyms: S-ROPIVACAINE HCL;(S)-ROPIVACAINE HYDROCHLORIDE;ROPIVACAINE HYDROCHLORIDE MONOHYDRATE;ROPIVCACAINE HYDROCHLORIDE;ROPIVACAINE HCL;(S)-1-propyl-2',6'-dimethylanilinoformoxylpiperidine monohydrochloride monohydrate;(S)-1-propyl-2',6'-dimethylanilinoformoxylpiperidine,monohydrochloride,monohydrate;(S)-Ropivaxaine hydrochloride 
CAS: 132112-35-7 
MF: C17H26N2O.ClH.H2O 
MW: 328.88 
 
Chemical Properties : White Solid 


Specification:

Product name: Articaine hydrochloride
Other Name methyl 4-methyl-3-[[(1-oxo-2-(propylamino)propyl]amino]-2-thenoate monohydrochloride;CarticaineHCl;Ultracaine;CARTICAINE HYDROCHLORIDE;Ultracain;Articaine hydrochloride;Methyl 4-methyl-3-(2-propylaminopropanoylamino)thiophene-2-carboxylate hydrochloride;4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylic acid methyl ester hydrochloride
Original China
CAS 23964-57-0
EINECS 245-957-7
Molecular formula C13H20N2O3S.ClH
Molecular Weight 320.839
Brand name NJBNSteroid
Delivery time within 24 hours upon receipt of payment
Delivery Fast and secure shipping by EMS, DHL, TNT, FedEx, UPS
Purity 99%
Package Discreet and Hidden package according to specific requirement
Appearance White powder
Certification SGS, ISO 9001, KOSHER
Payment Terms Western Union, Money Gram , T/T, Bitcoin
Minimum Order Quantity 10g
Price Negotiable
Usage It is used for pain control;
add to favorites Estradiol valerate CAS 979-32-8 as female hormone (jerryzhang001@chembj.com) 211100 Other
Estradiol valerate CAS 979-32-8 as female hormone

English Name: Estradiol valerate
Other Name: Oestradiol Valerate; estradiol-17-valerate
CAS: 979-32-8
EINECS Number: 213-559-2
Formula: C23H32O3
MW: 356.4984
Assay:99.8%
Appearance: White Crystalline powder
Uses: For the treatment of amenorrhea, menopausal symptoms, reduce milk secretion, prostate cancer;

2. Description
Estradiol valerate (EV, E2V) (INN, USAN, JAN) (brand names Altadiol,Deladiol, Delestrogen, Estraval, Lastrogen, Progynova, Valergen, many others), or oestradiol valerate (BAN), is a synthetic ester, specifically the 17-pentanoyl ester, of the natural estrogen, 17beta-estradiol. It was first introduced, as Delestrogen by Squibb in the United States, in 1954, and along with estradiol benzoate (1936) and estradiol cypionate (1952),has since become one of the most widely used esters of estradiol.

Medical Uses:
This medication is a female hormone (estrogen). It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. This medication may also be used by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure) and by men to treat prostate cancer.
Estradiol valerate is a female estrogen hormone. It works by replacing natural estrogens in a woman who can no longer produce enough estrogen.It works for advanced prostate cancer by antagonizing male hormones.

Dosage:
A single intramuscular injection of 4 mg estradiol valerate results in maximal plasma levels of estradiol of about 390 pg/mL within three days of administration, with levels declining to 100 pg/mL by 12–13 days. A study of high-dose combined administration of 40 mg estradiol valerate and 250 mg hydroxyprogesterone caproate in women once weekly for six months (described as a "pseudopregnancy" regimen) found that serum levels of estradiol increased from 27.8–34.8 pg/mL to 3028–3226 pg/mL after three months and to 2491–2552 pg/mL after six months of treatment.
add to favorites Riboflavin CAS 83-88-5 as food additive (jerryzhang001@chembj.com) 211100 Other
Riboflavin CAS 83-88-5 as food additive

Name: Riboflavin, Vitamin B2
Other name: Lactoflavine; Vitamin B2 (Riboflavine); Riboflavin Vitamin B2; E 101; Riboflavin (1.07609); Riboflavine; Vitamin B2 Feed Grade; Vitamin B_2; Vitamin B2; Riboflavin (VB2); 1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)pentitol; 5-deoxy-5-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-D-ribitol; 1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-D-ribitol; VITAMIN G; Riboflavin(VB2)
CAS No.: 83-88-5
EINECS No.: 201-507-1
M.F. : C17H20N4O6
M.W. : 376.3639
Appearance: Orange yellow crystalline powder;

2. What is Riboflavin (vitamin B2) ?
Riboflavin (vitamin B2) is part of the vitamin B group. It is the central component of the cofactors FAD and FMN and as such required for a variety of flavoprotein enzyme reactions including activation of other vitamins. It was formerly known as vitamin G.
As a chemical compound, riboflavin is a yellow-orange solid substance with poor solubility in water compared to other B vitamins. Visually, it imparts color to vitamin supplements (and bright yellow color to the urine of persons taking a lot of it).

Medical Uses:
Riboflavin has been used in several clinical and therapeutic situations. For over 30 years, riboflavin supplements have been used as part of the phototherapy treatment of neonatal jaundice. The light used to irradiate the infants breaks down not only bilirubin, the toxin causing the jaundice, but also the naturally occurring riboflavin within the infant's blood, so extra supplementation is necessary.

It is Used for recovery after illness and various diseases caused by lack of riboflavin. It is also used for prevention and control of the inflammation in mouth, eyes and externalia: Such as deficiency, cheilitis, glossitis, conjunctivitis and scrotitis, etc.

One clinical trial found that high-dose riboflavin appears to be useful alone or along with beta-blockers in the prevention of migraine. A dose of 400 mg daily has been used effectively in the prophylaxis of migraines, especially in combination with a daily supplement of magnesium citrate 500 mg.

Industrial Use:
Because riboflavin is fluorescent under UV light, dilute solutions (0.015-0.025% w/w) are often used to detect leaks or to demonstrate coverage in an industrial system such a chemical blend tank or bioreactor. (See the ASME BPE section on Testing and Inspection for additional details.)
add to favorites  Triamcinolone Acetonide CAS 76-25-5 Anti-inflammatory hormone (jerryzhang001@chembj.com) 211100 Other
 Triamcinolone Acetonide CAS 76-25-5 Anti-inflammatory hormone

Triamcinolone Acetonide
CAS: 76-25-5
MF: C24H31FO6
MW: 434.5
EINECS: 200-948-7
Type: Anti-inflammatory hormone 
Grade Standard:  Medicine Grade 
Apperance:  white or off-white powder 
Density: 1.33g/cm3 
Melting point::274-278℃ (dec.) Lead time:  1-3days Sample:  Available 
Packaging Details: 30mg/foil bag , or 50mg/bottle as your request 
Delivery Detail: within 2 days 
Appearance :white crystal  powder 
Storage:Store in a cool, dry place and keep away from direct strong light. hydrocortisone butyrate
Function: Anti-inflammatory hormone;

Description:
Triamcinolone acetonide is a kind of long-term glucocorticoid drugs.  It belongs to adrenocorticotropic hormone drugs. It is the derivative of Triamcinolone, and with the same function as Triamcinolone.
Triamcinolone acetonide, its acetate form appears to be white or white-like crystalline powder. The drug is odorless, with bitter taste. It is hardly soluble in water, slightly soluble in ethanol, soluble in chloroform, and slightly soluble in acetone.
Medical Function:
Clinically triamcinolone acetonide is used for treatment of various skin diseases such as atopic dermatitis, contact dermatitis, seborrheic dermatitis, neurodermatitis, eczema, psoriasis, psoriasis, lichen planus and skin pruritus, as well as bronchial asthma, rheumatoid arthritis, acute sprains, chronic ache in back and legs, frozen shoulder, tenosynovitis, ophthalmic inflammation, oral mucosal congestion, erosion, ulcers, granulomatous cheilitis, and oral mucosa chronic infectious diseases.
Furthermore, it can also be used for local injection treatment in keloid, cystic acne, discoid lupus erythematosus, alopecia areata and other small area of damages. Triamcinolone acetonide nasal spray can be used for the prevention and treatment of perennial, seasonal allergic rhinitis, and vasomotor rhinitis. Intra-articular injection of this drug can eliminate inflammation and pain, swelling or can alleviate, pain, stiffness and swelling feeling.
How it functions
Taking orally 5mg of the drug yields a bioavailability of about 23%. Its plasma concentration reaches peak (105 ng/mL) within one hour with the half-life is being 2 hours; It has a slow intramuscular absorption rate which takes effect within hours, and gives maximal effect within 1 to 2 days. The effect can be maintained for 2 ~ 3 weeks; the absorption rate of intradermal and intra-articular injection of the drug is low, but has a long-lasting effect; generally the efficacy can be maintained for more than 1-2 week per injection. This product has a low binding rate with plasma albumin protein, and is metabolized into non-active product in the liver, kidneys and tissues which is then further excreted by the kidneys. 
add to favorites Procaine CAS 59-46-1 for for local anesthesia (jerryzhang001@chembj.com) 211100 Other
Procaine CAS 59-46-1 for for local anesthesia

Procaine
CAS: 59-46-1
MF: C13H20N2O2
MW: 236.31
EINECS: 200-426-9
Usage: Procaine is a kind of local anesthetics. With low toxicity but quick and safe effects, procaine is suitable for local anesthesia, applied to the eye, ear, nose, teeth and other department operation, used for infiltration anesthesia, anesthesia and closed therapy supervisor. Procaine is also used in the production of procaine penicillin.



Description

Procaine is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade name Novocain, in some regions procaine is referred to generically as novocaine.
It acts mainly as a sodium channel blocker. Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.

Medical Application:
Procaine is a kind of local anesthetics. With low toxicity but quick and safe effects, procaine is suitable for local anesthesia, applied to the eye, ear, nose, teeth and other department operation, used for infiltration anesthesia, anesthesia and closed therapy supervisor. Procaine is also used in the production of procaine penicillin.
A 1% procaine injection has been recommended for the treatment of extravasation complications associated with venipuncture (along with moist heat, ASA, steroids, antibiotics). It has likewise been recommended for treatment of inadvertent intra-arterial injections (10 ml of 1% procaine), as it helps relieve pain and vascular spasm.
Procaine is used as an injection during surgery and other medical and dental procedures.
add to favorites  Imiquimod CAS  99011-02-6 for Treatment of adult genital and perianal warts   (jerryzhang001@chembj.com) 211100 Other
 Imiquimod CAS  99011-02-6 for Treatment of adult genital and perianal warts

Product Name:    Imiquimod
Synonyms:    R-837;S-26308;1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLIN-4-AMINE;4-amino-1-isobutyl-1h-imidazo[4,5-c]quinoline;ALDARA;IMIQUIMOD;1-isoButyl-1H-Inudazole[4.5-c]quinoline-4-amine;1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine, R-837, S-26308, Aldara
CAS:    99011-02-6
MF:    C14H16N4
MW:    240.3
Mol File:    99011-02-6.mol ;

Description:
Imiquimod is a kind of imidozoquinoline amine-class interleukin agonist developed by the 3M Pharmaceuticals Company (US), belonging to the drug for the treatment of genital warts. Upon being applied to the mice skin, it can induce the cytokinesis and produce 伪-interferon, tumor necrosis factor and many kinds of interleukins.
Imiquimod itself has no direct effect on the virus itself, but instead through stimulating the body for producing cytokines and stimulating immune response to eliminate the wart tissue and reduce the viral erosion. 

Medical Function:
Clinically, Imiquimod can be used as the immunomodulators in the treatment of adult genital and perianal warts with convenient application, well tolerance and unique mechanism of action which makes it be the first-choice drug for treatment of genital warts. In addition, there are reports that imiquimod can be used for treating viral skin diseases including common warts, flat warts, molluscum and herpes simplex virus.
It can also be effective in treating basal cell carcinoma, Bowen's disease, Bowen papulosis, actinic keratosis, and skin tumors such as cutaneous T-cell tumor and Kaposi's sarcoma. It may also be effective in treating vitiligo and alopecia areata. 

Usage and Dosage
It can be used for the treatment of adult external genital and perianal genital warts at 3 times per week. Just before sleep, first apply the product evenly in a thin layer on the surface of the wart and gently massage until the product is completely absorbed.
The position of the medication should not be packeted and should be maintained for 6 to 10 hours, and then wash with a neutral soap and clean water for clearing the drugs in the administration site. Wash your hands before and after treatment. 250 mg of cream can be applied to 20cm2 of wart. Avoid excessive application of the drug. Patients should continue the treatment until the wart is completely cleared.
Wart can be cleared within 2-4 week at the fastest speed and can be generally cleared within 8 to 12 weeks. The medication should be not more than 16 weeks. After the treatment, patients with mild erythema locally who does not have to be discontinued for drug; if the patients feel general malaise or get local skin reactions (edema, erosion, pain, etc.), the drug should be discontinued. Only when the reaction is alleviated can they continue the medication.
add to favorites Cloxacillin sodium CAS 7081-44-9 for the treatment of a number of bacterial infections (jerryzhang001@chembj.com) 211100 Other
Cloxacillin sodium CAS 7081-44-9 for the treatment of a number of bacterial infections
 
Product Name: Cloxacillin sodium
Synonyms:bactopen;brl-1621sodiumsaltmonohydrate;cloxacillinsodiummonohydrate;orbeninsodiumhydrate;prostaphlin-amonohydrate;sodiumcloxacillinmonohydrate;staphobristol-250;thyl-4-isoxazolecarboxamido)-3,3-dimethyl-7-oxo-,sodiumsalt,monohydrate
CAS:7081-44-9
MF:C19H19ClN3NaO6S
MW:475.88
EINECS:211-390-9;

1. What is Cloxacillin ?
Cloxacillin is an antibiotic useful for the treatment of a number of bacterial infections. It is semisynthetic and in the same class as penicillin.
Cloxacillin sodium is an antibiotic medication commonly used to treat infections with Staphylococcus bacteria. It has a low risk of side effects, except for a potentially serious allergic reaction in a small number of patients. Before someone starts using cloxacillin sodium, it is advisable to discuss medical history with a medical professional to determine if there are any obvious risk factors for a bad reaction. Another drug may need to be considered to treat the infection.
This medication is in the penicillin family, and is produced through semi-synthetic means. It works by attacking the process bacteria use to synthesize their cell walls, killing them and effectively stopping the infection. The dosage is given orally and may vary depending on the specifics of the infection and the patient’s weight. An adjustment for a patient with kidney impairment may also be necessary, as these patients can’t clear this medication as quickly and require a lower dose.
Usage:
Cloxacillin is used against staphylococci that produce beta-lactamase, due to its large R chain, which does not allow the beta-lactamases to bind. This drug has a weaker antibacterial activity than benzylpenicillin, and is devoid of serious toxicity except for allergic reactions.
Cloxacillin was discovered and developed by Beecham.It is sold under a number of trade names, including Cloxapen, Cloxacap, Tegopen and Orbenin. It is on the World Health Organization's List of Essential Medicines, the most important medication needed in a basic health system.
Cloxacillin is used to treat a wide variety of bacterial infections. This medication is a type of penicillin antibiotic. It works by stopping the growth of bacteria.
This antibiotic treats only bacterial infections. It will not work for viral infections (e.g.,common cold, flu). Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness.
add to favorites Clobetasol Propionate CAS 25122-46-7 for treatment of the inflammatory and pruritic manifestations (jerryzhang001@chembj.com) 211100 Other
Clobetasol Propionate CAS 25122-46-7 for treatment of the inflammatory and pruritic manifestations

Product Name: Clobetasol Propionate
Synonyms:17-propionate;cgp9555;clobesol;pregna-1,4-diene-3,20-dione,21-chloro-9-fluoro-11-beta,17-dihydroxy-16-beta-me;CLOBESTASOL PROPIONATE;CLOBETASOL-17-PROPIONATE;CLOBETASOLE PROPIONATE;CLOBETASOL PROPIONATE
CAS No.: 25122-46-7
EINECS: 246-634-3
Molecular Formula: C25H32ClFO5
Formula Weight: 466.97
Appearance: White Crystalline Powder
Assay: 99.65%
Packaging and storage:  Preserve in well-closed containers, and store at controlled room temperature.
Usage: For short-term topical treatment of the inflammatory and pruritic manifestations of moderate to severe corticosteroid-responsive dermatoses of the scalp.

2. Description:
Clobetasol propionate  is a corticosteroid of the glucocorticoid class used to treat various skin disorders including eczema and psoriasis. It is also highly effective for contact dermatitis caused by exposure to poison ivy/oak. Clobetasol belongs to US Class I (Europe: class IV) of the corticosteroids, making it one of the most potent available. It comes in shampoo, mousse, ointment and emollient cream presentations. It has very high potency and typically should not be used with occlusive dressings, or for extended continuous use (beyond two weeks). It is also used to treat several autoimmune diseases including alopecia areata, vitiligo, lichen sclerosus, and lichen planus.

Clobetasol propionate is a corticosteroid of the glucocorticoid class used to treat various skin disorders including eczema and psoriasis. It is also highly effective for contact dermatitis caused by exposure to poison ivy/oak. Clobetasol belongs to US Class I (Europe: class IV) of the corticosteroids, making it one of the most potent available.
 
It comes in shampoo, mousse, ointment and emollient cream presentations. It has very high potency and typically should not be used with occlusive dressings, or for extended continuous use (beyond two weeks). It is also used to treat several auto-immune diseases including alopecia areata, vitiligo and lichen planus (auto immune skin nodules).
 
Clobetasol propionate for synthetic efficient local external use sugar cortical hormone drugs. With strong anti-inflammatory, resistance to itch and capillary shrinkage effect, its anti-inflammatory effects of about 112.5 times of hydrocortisone sodium, betamethasone dipropionate ramification 2.3 times, fluocinolone 18.7 times. At the same time a suppression of mitosis Use, can effectively penetrate into skin cutin layer.

As a type of steroid that is applied to the skin, clobetasol topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions. The solution are used for scalp problems, the foam is used for mild to moderate plaque psoriasis, the cream, lotion, and spray are used for moderate to severe plaque psoriasis, and the foam and shampoo are used for moderate to severe scalp psoriasis.

Application:
This medicine is a corticosteroid (cortisone-like medicine or steroid). belongs to a group of medications known as topical steroids and is used to treat inflammation and itching due to a wide variety of skin conditions, such as eczema, psoriasis, dermatitis, and allergic reactions.
 
Clobetasol propionate is a synthetic corticosteroid, for topical dermatologic use. Clobetasol, an analog of prednisolone, has a high degree of glucocorticoid activity and a slight degree of mineralocorticoid activity.
add to favorites Mometasone Furoate CAS 83919-23-7 for anti-inflammatory (jerryzhang001@chembj.com) 211100 Other
Mometasone Furoate CAS 83919-23-7 for anti-inflammatory

Mometasone Furoate
CAS: 83919-23-7
MF: C27H30Cl2O6
MW: 521.43
Purity: 99%
Package: 1kg/aluminum cans
Appearance: White powder.
USES: Use of corticosteroids in local effect, have anti-inflammatory, relieving itching and vascular contraction effect. For patients with skin diseases, can alleviate inflammation and itching, especially with the reaction of the patients have cortisone.

Description
Mometasone furoate is a glucocorticosteroid used topically to reduce inflammation of the skin or in the airways. It is a prodrug of the free form mometasone.
Mometasone furoate is a synthetic (man-made) steroid hormone in the glucocorticoid family of steroid hormones that is used for the treatment of nasal allergy. The naturally occurring glucocorticoid hormone is cortisol or hydrocortisone which is produced in the adrenal glands. Glucocorticoid hormones are potent reducers of inflammation (anti-inflammatory). When used as a nasal inhaler or spray, medications travel directly to the inner lining of the nose, and very little is absorbed into the body to cause side effects. The FDA approved mometasone in October 1997.

Medical Uses:
Mometasone furoate is used in the treatment of inflammatory skin disorders (such as eczema and psoriasis) (topical form), allergic rhinitis (such as hay fever) (topical form), asthma (inhalation form) for patients unresponsive to less potent corticosteroids, and penile phimosis. In terms of steroid strength, it is more potent than hydrocortisone, and less potent than dexamethasone.
This medication is used to treat skin conditions such as eczema, psoriasis, allergies, andrash. Mometasone decreases swelling (inflammation), itching, and redness. Mometasone is a medium-strength corticosteroid. This medication is available in several forms including cream, ointment, and lotion (solution). Your doctor will choose the type of product based on the skin condition/area of the body being treated.
Nasal mometasone is employed in adults (including the elderly) and children over 2 years, diminishing the symptoms such as hay fever (seasonal allergic rhinitis) and other allergies (perennial rhinitis), including nasal congestion, discharge, pruritus, and sneezing. It can be used two to four weeks before pollen season, reducing the severity of symptoms. It is also indicated for the treatment of nasal polyps and symptoms associated with including congestion and hyposmia in patients over the age of 18. It can also produce nasal drip, a sensation of tickling in the throat, and loss of the sense of taste and smell.
4. Application fields:
1. Biochemical studies, adrenal cortical hormone drugs.
2. Glucocorticoids have anti-inflammatory, anti allergic, anti toxin, anti shock four role.
3. Adrenal corticoids
add to favorites Glutathione CAS 70-18-8 for Skin Care (jerryzhang001@chembj.com) 211100 Other
Glutathione CAS 70-18-8 for Skin Care

Glutathione
Alias:REDUCEDGLUTATHIONE;copren;deltathione;Glutathion;glutathionesh;glutatiol;glutatione;glutide
CAS: 70-18-8
EINECS: 200-725-4
Formula: C20H32N6O12S2
Molecular Weight: 612.63
Appearance: white powder
Content: 99%
Uses: Glutathione is a peptide composed of three amino acids present in almost every cell in the body, especially the liver cells. Protect the liver cell membrane and promote the role of the liver enzyme activity, and many toxic chemicals play a role in detoxification combined. A variety of reasons for liver poisoning, alcoholism caused by the injury, cirrhosis and other diseases have a good effect. Mainly for biochemical reagents, antidotes, mainly for heavy metals, fluoride, carbon monoxide and other toxic organic solvents.


Medical Function:
The Functions of Glutathione are antioxidant, scavenging free radicals, detoxification, enhance immunity, anti-aging, anti-cancer, anti radiation damage, and other functions. It also helps white blood cells to kill bacteria and prevent the oxidation of the vitamins C and E, to prevent stroke and cataract formation. In addition, glutathione can bind the carcinogen, than excrete them through the urine in vitro. 
Enhancing the immune system:
Body' s immune activity, involving unimpeded multiplication of lymphocytes and antibody production, requires maintenance of normal levels of glutathione inside the lymphocytes.

Antioxidant and free radical scavenger:
Glutathione plays a central protective role against the damaging effects of bacteria, viruses, pollutants and free radicals.

Regulator of other antioxidants:
Without glutathione, other important antioxidants such as vitamins C and E cannot do their job adequately to protect your body against disease.

Detoxifying agent:
Another major function of glutathione is in the detoxification of foreign chemical compounds such as carcinogens and harmful metabolites.

Skin whitening:
Dermatologists prescribe Glutathione for its only side effect: Whitening of dark skin. People with darker skin tone report that taking Glutathione capsules along with vitamin C for three to six months or more actually lightens the color of their skin.
add to favorites Ropivacaine hydrochloride CAS 132112-35-7  (jerryzhang001@chembj.com) 211100 Other
Phenacetin CAS 62-44-2 as local anesthetic used topically in opthalmology

Phenacetin English Synonyms:
1-ACETYL-P-PHENETIDIN;4-ACETOPHENETIDIDE;4-acetophenetidine;4'-ETHOXYACETANILIDE;4-ETHOXYACETANILIDE;ACETOPHENETIDIN;ACETOPHENETIDINE;ACET-P-PHENETIDINECAS NO.: 62-44-2
EINECS:200-533-0
Assay: 98%
Molecular Formula: C10H13NO2
Molecular Weight: 179.22
Packing: foil bag/tin
Chemical Properties: White crystalline powder
Usage :Analgesic, antipyretic. Component of APC tablets, analgesic mixture also containing aspirin and caffeine. 

2.What is Tetracaine HCl?
Phenacetin (or acetophenetidin) is a pain-relieving and fever-reducingdrug, which was widely used between its introduction in 1887.
Phenacetin was introduced in 1887 in Elberfeld by German company Bayer, and was used principally as an analgesic; it was one of the first synthetic fever reducers to go on the market. It is also known historically to be one of the first non-opioid analgesics without anti-inflammatory properties.

Medical Uses:

The antipyretic and analgesic effects of phenacetin are similar to that of acetylsalicylic acid, which is mainly used as anti-inflammatory drugs with a slow and long-lasting effect. It is an effective drug on the treatment of headache, neuralgia, joint pain and fever. However, it has a weak effect on treating anti-rheumatic, anti-inflammatory. Overdose can cause methemoglobinemia, resulting in hypoxia. 
1. Used for organic synthesis of raw materials and drug intermediates from acetaminophen ether. 
2. Antipyretic analgesics for the treatment of fever, headache, neuralgia.
3. Active pharmaceutical ingredient for Scientific Research.
add to favorites  Desonide CAS  638-94-8  for Anti-inflammatory Treatment  (jerryzhang001@chembj.com) 211100 Other
 Desonide CAS  638-94-8  for Anti-inflammatory Treatment

Desonide
English Synonyms: DESONIDE;1,4-PREGNADIEN-11-BETA, 16-ALPHA, 17,21-TETROL-3,20-DIONE 16,17-ACETONIDE;(11b,16a)-11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-pregna-1,4-diene-3,20-dione;16-alpha-hydroxyprednisole-16,17-acetonide;17-acetonide,16-alpha-hydroxy-prednisolone-1;d-2083;steroderm 
CAS NO.:  638-94-8 
Assay: 99%
Molecular Formula: C24H32O6 
Molecular Weight: 416.51 
Appearance: White powder
Packing:foil bag
Usage: With acetal-based adrenal cortex hormones
How to use s-desonide topical: Use this medication only on the skin.

Description:
Desonide is the generic name of a low-potency topical corticosteroid anti-inflammatory that has been available since the 1970s. It is primarily used to treat atopic dermatitis (eczema), seborrheic dermatitis, contact dermatitis and psoriasis in both adults and children. It has a fairly good safety profile and is available as a cream, ointment, lotion, and as a foam under the tradename Verdeso Foam. Other trade names for creams, lotions, and ointments include Tridesilon, DesOwen, Desonate. It is a group VI corticosteroid under US classification, the second least potent group.
Chemically, Desonide, the active ingredient in Desonide Ointment, 0.05% is C24H32O6. It has the following structural formula:
The molecular weight of Desonide is 416.51. It is a white to off-white powder. The solubility of Desonide in distilled water saturated with ether is 184 mg/L.
Each gram of Desonide Ointment, 0.05% contains 0.5 milligram of Desonide microdispersed in a base of white petrolatum.

Medical Function:
Desonide is a prescription topical treatment for redness, swelling, itching, and discomfort of various skin conditions. Regardless of the vehicle used, desonide is applied 2 to 3 times a day, at the same times each day. Skin conditions typically improve in the first two weeks of treatment. Patients are instructed to use desonide for the minimum amount of time necessary for conditions to improve.
Endogenous eczema clinical cure rate, the overall curative effect is distinct, and the low Incidence of adverse reactions, is a safe and effective external cortex hormone.
Wash your hands. Before applying the medication, clean and dry the affected area. Apply a thin film of the medication to the affected area and gently rub in, usually 2-3 times daily, or as directed by your doctor. If using the gel, apply the gel usually only 2 times daily. Do not bandage, wrap, or cover the area unless you are instructed to do so by your doctor. If used in the diaper area on an infant, do not use tight-fitting diapers or plastic pants.
After applying the medication, wash and dry your hands, unless you are using this medication to treat the hands. When applying this medication near the eyes, avoid getting it in the eyes because this may worsen or cause glaucoma, or cause irritation. Also, avoid getting this medication in the nose or mouth. If you get this medication in your eyes, nose, or mouth, rinse immediately with plenty of water.
add to favorites Ulipristal acetate CAS 126784-99-4  (jerryzhang001@chembj.com) 211100 Other
Ulipristal acetate CAS 126784-99-4 

Ulipristal acetate

Synonym: EllaOne, Ulipristal ace
CAS: 126784-99-4
M.F.: C28H35NO3
M.W.: 433.5824
Appearance: White crystalline powder
Usage: contraceptive medicine anabolic powder
Storage: Kept Ulipristal acetate in a cool, dry and ventilated place
We guarantee good quality products. 100% refunded if parcel is not delivered or poor quality.


Description
Ulipristal acetate (trade name EllaOne in the European Union, Ella in the U.S. for contraception, and Esmya for uterine fibroid) is a selective progesterone receptor modulator (SPRM).

Medical Uses
Emergency contraception:
For emergency contraception a 30 mg tablet is used within 120 hours (5 days) after an unprotected intercourse or contraceptive failure. It has been shown to prevent about 62–85% of expected pregnancies, and prevents more pregnancies than emergency contraception with levonorgestrel. Ulipristal acetate is available by prescription for emergency contraception in over 50 countries, with access through pharmacists without a prescription being tested in the United Kingdom. From July 2016 available without prescription in Israel.
Treatment of uterine fibroids
Ulipristal acetate is used for pre-operative treatment of moderate to severe symptoms of uterine fibroids in adult women of reproductive age in a daily dose of a 5 mg tablet.
Treatment of uterine fibroids with ulipristal acetate for 13 weeks effectively controlled excessive bleeding due to uterine fibroids and reduced the size of the fibroids.
Two intermittent 3-months treatment courses of ulipristal acetate 10 mg resulted in amenorrhea at the end of the first treatment course in 79.5%, at the end of the second course in 88.5% of subjects. Mean myoma volume reduction observed during the first treatment course (−41.9%) was maintained during the second one (−43.7%). After two to four 3-months courses of treatment, UPA-treated fibroids shown about -70% in volume reduction. This phenomenon was temptatively explained by the combination of multifactorial events involving control of proliferation of the tumor cells, induction of apoptosis and remodeling of the extracellular matrix.
add to favorites Tanning Skin Helpers Melanotan II CAS 121062-08-6 (jerryzhang001@chembj.com) 211100 Other
Tanning Skin Helpers Melanotan II CAS 121062-08-6

Melanotan II
 
Cas No.: 121062-08-6
Sequence: Ac-NLE-c[ASP-His-d-PHE-ARG-TRP-LYS]-NH2  Chemical Bridge Asp2-Lys7
Purity (HPLC): 98.0%
Appearance: White powder
Molecular Formula: C50H69N15O9
Molecular Weight: 1024.18
Single Impurity (HPLC): 0.5%max
Amino Acid Composition: ±10% of theoretical
Peptide Content (N%): ≥80.0%
Water Content(Karl Fischer): ≤8.0%
Acetate Content(HPIC): ≤10.0%
Specific Rotation (20/D): -55.0~-65.0°(c=1 1%HAc)
MS(ESI): Consistent
Mass Balance: 95.0~105.0%;

1. Description

Melanotan II is a cyclic lactam analog of the melanocortin alpha-Melanocyte Stimulating Hormone (alpha-MSH), a multifunctional peptide that regulates a broad array of physiological functions, including the stimulation of melanogenesis and aphrodisiac effects via melanocyte receptor activation.
It has been studied extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis stimulating properties.
Melanotan II could be used to stimulate skin melanogenesis and development as a photoprotective or cosmetic drug. Additionally, Melanotan II and a similar alpha-MSH analogue, know as PT-141 or Bremelanotide, have been studied at length as a potential remedy for the treatment of sexual dysfunction; specifically, male erectile dysfunction.

How it works?
This peptide is a designed to stimulate the body's tanning response with minimal exposure to sunlight. This can be a wonderful way for those with fair to very fair skin to get tanned without having to spend weeks in the sun and going through the burn and heal process.
By using MT2, users experience quicker tanning and and faster healing to damaged skin cells than would otherwise be possible. Because of this, it is especially suited to those who's skin is pale; those who are at greatest risk of developing skin cancer.
add to favorites Estriol CAS 50-27-1 for  treating menopausal syndrom (jerryzhang001@chembj.com) 211100 Other
Estriol CAS 50-27-1 for  treating menopausal syndrom

Estriol
Synonyms: Oestriol; 1, 3, 5(10)-Estratriene-3, 16a, 17b-triol CAS: 979-32-8
CAS No.: 50-27-1
ECNECS No.: 200-022-2
MF: C18H24O3
MW: 288.3814
Purity: 99%min
Melting Point: 281-282º C
Boiling Point: 469 ºC at 760 mmHg
Refractive Index: 1.624
Flash Point: 220.8 ºC
Density: 1.255g/cm3
Appearance: White crystalline powder
Grade: Pharmaceutical Grade
Storage: Shading, confined preservation
Lead time: Within 12 hours upon receipt of payment
Delivery: EMS, DHL, TNT, FedEx, UPS
Usage: A metabolite of Estradiol. An estrogenic metabolite considerably less potent than the hormone Estradiol. Pharmaceutical material, Steroid hormone, estrogen.

2. Description:
Estriol belongs to natural hormone and is the metabolite of estradiol in vivo. It is mainly presented in the urine. Estrogen has a relative small activity with the oral activity being 6 times as high as estrone but being weaker than estradiol with non-carcinogenic effects. After its administration, the in vivo estradiol levels did not change. 
Estriol has selective action on the vaginal and cervical canal but has no effect on the uterus and endometrium entity. Animal experiments have shown that estriol has a stronger effect on vaginal epithelial keratosis than estradiol, thus being able to promote vaginal epithelial hyperplasia, superficial cells keratosis, mucosal angiogenesis and vaginal epithelial wound healing, but having a weak effect on the weight gain of mouse uterus.
At the same time, estriol can enhance the function of cervix cell, causing the cervix muscle fiber hyperplasia and increasing the cervical elasticity and softness.
Estriol also has significant effect on the hematopoietic system and can reduce vascular permeability and fragility. Therefore, it can be used for the treatment of various kinds of hemorrhage. It also has effect of rapidly increasing the peripheral leukocytes and generally begins to take effect at 1 to 3 days after treatment but with a shorter duration of action and is effective in treatment the leukopenia induced by radiotherapy and chemotherapy. 

Medical Function:
1.It can be used for treating cervicitis and especially suitable for treating menopausal syndrome and senile vaginitis. 
2. It can also be used as the adjuvant drug for middle-term labor induction and artificial abortion. 3. It can also be used for treating prostatic hypertrophy and prostate cancer.
4. It still has a rapid role in increasing the peripheral leukocytes. It generally takes effect at 1 to 3 days after the treatment but with a short duration period. It also has efficacy in treating leukopenia caused by chemotherapy or radiotherapy.
5. It can be used for reducing the vascular permeability and fragility and can be used for the treatment of various kinds of hemorrhage. It also has quick hemostasis effect on menorrhagia, hysterectomy or tonsillectomy.
2.Application:
It belongs to estrogen drug. It can be used for treating leukopenia, various kinds of menopathy, senile vaginitis, and menopausal syndrome. You may also get temporary breast swelling and lumps, menstrual cycle disorders with self-recovery after stopping the drug for about 1 month. Patients of breast hyperplasia, breast lumps, and cancer potentially being related to female hormone-related cancer, aplastic anemia and liver disease patients should be disabled.
add to favorites Dexamethasone CAS 50-02-2 for  inflammatory and autoimmune Treatment (jerryzhang001@chembj.com) 211100 Other
Super Pure 99% Dexamethasone CAS 50-02-2 for  inflammatory and autoimmune Treatment

1.Quick Detail:


Product name Dexamethasone
Other Name Fluormone; Fluorocort; Gammacorten; HL-Dex; Hexadecadrol; Hexadrol
Original China
CAS 50-02-2
ENIECS 200-003-9
Molecular formula C22H29FO5
MW 392.46
Brand name NJBNSteroid
Leading time within 24 hours upon receipt of payment
Delivery Fast and secure shipping by EMS, DHL, TNT, FedEx, UPS
Purity 98.8%
Package Discreet and Hidden package according to specific requirement
Appearance Off-White Powder
MP 262-264 °C
Certification SGS, ISO 9001, KOSHER
Payment Terms Western Union, Money Gram , T/T, Bitcoin
Minimum Order Quantity 5g
Price Negotiable
Usage Dexamethasone is a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthas e.

Description:
Dexamethasone is a type of steroid medication. It is used in the treatment of many conditions, including rheumatic problems, a number ofskin diseases, severe allergies, asthma, chronic obstructive lung disease,croup, brain swelling, and along with antibiotics in tuberculosis. In adrenocortical insufficiency it should be used together with a medication that has greater mineralocorticoid effects such as fludrocortisone. In preterm labor it may be used to improve outcomes in the baby. It may be taken by mouth, as an injection into a muscle, or intravenously. The effects of dexamethasone are frequently seen within a day and last for about three days.

The long term use of dexamethasone may result in thrush, bone loss, cataracts, easy bruising, or muscle weakness. It is pregnancy category C in the United States meaning use should be based on benefits being predicted to be greater than risks. In Australia it is class A, meaning it has been frequently used in pregnancy and not been found to cause problems to the baby. It should not be taken when breastfeeding.Dexamethasone has anti-inflammatory and immunosuppressant effects.

4.Application:
Dexamethasone is used to treat many inflammatory and autoimmune conditions, such as rheumatoid arthritis and bronchospasm. Idiopathic thrombocytopenic purpura, a decrease in numbers of platelets due to an immune problem, responds to 40 mg daily for four days; it may be administered in 14-day cycles. It is unclear whether dexamethasone in this condition is significantly better than other glucocorticoids.
Cancer patients undergoing chemotherapy are given dexamethasone to counteract certain side effects of their antitumor treatments. Dexamethasone can augment the antiemetic effect of 5-HT3 receptor antagonists, such as ondansetron.In brain tumors (primary or metastatic), dexamethasone is used to counteract the development of edema, which could eventually compress other brain structures. It is also given in cord compression, where a tumor is compressing the spinal cord.
Dexamethasone may be given to women at risk of delivering prematurely to promote maturation of the fetus' lungs. This has been associated with low birth weight, although not with increased rates of neonatal death.Dexamethasone has been also been used during pregnancy as an off-label prenatal treatment for the symptoms of congenital adrenal hyperplasia (CAH) in female fetuses. CAH causes a variety of physical abnormalities, notablyambiguous genitalia in girls. Early prenatal CAH treatment has been shown to reduce some CAH symptoms, but it does not treat the underlying congenital disorder.
Dexamethasone is the treatment for the very rare disorder of glucocorticoid resistance. In adrenal insufficiency and Addison's disease, dexamethasone is prescribed when the patient does not respond well to prednisone or methylprednisolone.
add to favorites Prilocaine CAS 721-50-6 (jerryzhang001@chembj.com) 211100 Other
Prilocaine CAS 721-50-6

Synonyms: 2-(propylamino)-o-propionotoluidid;
CAS: 721-50-6
MF: C13H20N2O
MW: 220.31
EINECS: 211-957-0
Product Categories: Active Pharmaceutical Ingredients
Packing:Foil bag or as requirments;

Description

Prilocaine is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Löfgren. In its injectable form (trade name Citanest), it is often used in dentistry. It is also often combined with lidocaine as a topical preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia (IVRA).

Prilocaine belongs to amide local anesthetic drug with its anesthesia intensity and speed being similar as lidocaine but with a longer duration period and weaker effect on vasodilation. It has a lower toxicity than lidocaine. It is clinically for local anesthesia, especially suitable for treating patients who are not allowed to use adrenaline. 

In some patients, a metabolite of prilocaine may cause the unusual side effect of methemoglobinemia, which may be treated with methylene blue. 

Local anesthetic is a substance that causes loss of sensation only to the area to which it is applied without affecting consciousness. Most local anesthetics structures have amino-ester or an amino-amide group which are linked to hydrophilic (secondary or tertiary amine) and to hydrophobic group (aromatics) on the other side. 

Local anesthetics, long duration, lower toxicity, chemicals that are also small Suitable for epidural anesthesia, block anesthesia and infiltration anesthesia, etc. 

Application:
It is a kind of local anesthetic drug. The product has better efficacy than procaine and the local anesthesia intensity and speed being similar as lidocaine but with longer duration time and less toxicity as well as smaller accumulation effect. It is suitable for epidural anesthesia, conduction anesthesia and infiltration anesthesia.
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